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Argininosuccinate synthase : ウィキペディア英語版 | Argininosuccinate synthase
Argininosuccinate synthase or synthetase (ASS; ) is an enzyme that catalyzes the synthesis of argininosuccinate from citrulline and aspartate. ASS is responsible for the third step of the urea cycle and one of the reactions of the citrulline-NO cycle. ==Genetic structure== The gene that encodes for this enzyme, ''ASS'', is located on chromosome 9. In humans, ''ASS'' is expressed mostly in the cells of liver and kidney. The expressed ASS gene is at least 65 kb in length, including at least 12 introns.
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